Fermentation Broth Clarification

Fermentation broth can contain microorganisms, cell debris, protein aggregates and other suspended solids that must be removed before purification, concentration or downstream processing. Effective clarification improves process stability and helps protect sensitive downstream equipment.

UNITE provides filtration solutions for bio-processing applications. Candle Filters can support high-efficiency solid-liquid separation where fine particles and filter-cake handling are important. For process lines requiring integrated systems, see the Filtration System Series.

Common Fermentation Clarification Challenges

• High solids loads can cause rapid filter blockage
• Biomass and fine particles may be difficult to separate
• Product recovery and process hygiene are important

Recommended Filtration Solutions

The equipment should be selected based on broth viscosity, solids concentration, desired filtrate clarity and production capacity.

Get a Customized Fermentation Filtration Solution

UNITE can develop filtration systems for fermentation broth clarification, biomass separation and bio-processing applications.